Publications

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15. Intrinsic properties of human germinal center B cells set antigen affinity thresholds

K. Kwak, N. Quizon, H. Sohn, A. Saniee, J. Manzella-Lapeira, P. Holla, J. Brzostowski, J. Lu, H. Xie, C. Xu, K. M. Spillane, P. Tolar, and S. K. Pierce

Science Immunology 3, eaau6598 (2018).

14. Mechanics of antigen extraction in the B cell synapse

KM Spillane and P Tolar

Molecular Immunology 101, 319-328 (2018).

13. Evidence for a vibrational phase-dependent isotope effect on the photochemistry of vision

C Schnedermann, X Yang, M Liebel, KM Spillane, J Lugtenburg, I Fernández, A Valentini, I Schapiro, M Olivucci, P Kukura, and RA Mathies

Nature Chemistry 10, 449-455 (2018).

12. DNA-based probes for measuring mechanical forces in cell-cell contacts: Application to B cell antigen extraction from immune synapses

KM Spillane and P Tolar

Methods in Molecular Biology 1707, 69-80 (2018).

11. Functionalisation of detonation nanodiamond for monodispersed, soluble DNA-nanodiamond conjugates using mixed silane bead-assisted sonication disintegration

R Edgington, KM Spillane, G Papageorgiou, W Wray, H Ishiwata, M Labarca, S Leal-Ortiz, G Reid, M Webb, J Foord, N Melosh, and AT Schaefer

Scientific Reports 8, 728 (2018).

10. B cell antigen extraction is regulated by physical properties of antigen-presenting cells

KM Spillane and P Tolar

The Journal of Cell Biology 216, 217-230 (2017).

9. Germinal center B cells recognize antigen through a specialized immune synapse architecture

CR Nowosad, KM Spillane, and P Tolar

Nature Immunology 17, 870-877 (2016).

8. High-speed single-particle tracking of GM1 in model membranes reveals anomalous diffusion due to interleaflet coupling and molecular pinning

KM Spillane*, J Ortega-Arroyo*, G de Wit, C Eggeling, H Ewers, MI Wallace, and P Kukura

Nano Letters 14, 5390-5397 (2014). (*co-first authors)

7. Label-free, all-optical detection, imaging, and tracking of a single protein

J Ortega-Arroyo, J Andrecka, KM Spillane, N Billington, Y Takagi, JR Sellers, and P Kukura

Nano Letters 14, 2065-2070 (2014).

6. Wavepacket splitting and two‐pathway deactivation in the photoexcited visual pigment isorhodopsin

D Polli, O Weingart, D Brida, E Poli, M Maiuri, KM Spillane, A Bottoni, P Kukura, RA Mathies, G Cerullo, and M Garavelli

Angewandte Chemie Int. Ed. 53, 2504-2507 (2014).

5. Force generation in B-cell synapses: Mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination

P Tolar and KM Spillane

Advances in Immunology 123, 69-100 (2014).

4. Direct observation and control of supported lipid bilayer formation with interferometric scattering microscopy

J Andrecka, KM Spillane, J Ortega-Arroyo, and P Kukura

ACS Nano 7, 10662-10670 (2013).

3. Conformational homogeneity and excited-state isomerization dynamics of the bilin chromophore in phytochrome Cph1 from resonance Raman intensities

KM Spillane, J Dasgupta, and RA Mathies

Biophysical Journal 102, 709-717 (2012).

2. Conical intersection dynamics of the primary photoisomerization event in vision

D Polli, P Altoe, O Weingart, KM Spillane, C Manzoni, D Brida, G Tomasello, G Orlandi, P Kukura, RA Mathies, M Garavelli, and G Cerullo

Nature 467, 440-443 (2010).

1. Homogeneity of phytochrome Cph1 vibronic absorption revealed by resonance Raman intensity analysis

KM Spillane, J Dasgupta, JC Lagarias, and RA Mathies

Journal of the American Chemical Society 131, 13946-13948 (2009).